HIV and the Antiviral Role of Mushroom Nutraceuticals


  • Prof Dr Tito FERNANDES CIISA, FMV, University of Lisbon
  • Eusébio Chaquisse Departamento de Saúde da Comunidade, Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique
  • Jorge Ferrão Universidade Pedagógica de Maputo, Rua João Carlos Raposo Beirão 135, Maputo, Mozambique



mushrooms; HIV; immunoceuticals; antiviral activity; bioactive compounds


Mushrooms, environment and human health are interconnected. Mushrooms’ essential role in the environment and bioremediation have attracted market attention because they are also a potential source of bioactive compounds able to perform several functions in organisms with benefits for the health of the consumer. The HIV/AIDS epidemic poses an inescapable challenge to the world at large and to Africa in particular and more specifically in Mozambique. A brief outline of the historical background discusses the present knowledge of mushrooms containing antiviral factors. Antiviral factors generally do not destroy their target pathogen; rather, they inhibit the development or reproduction of the virus. Administration of mushrooms, also used as dietary supplement extracts or biomass, supplies active immunoceuticals that may block virus cell-to-cell infection, modify viral receptors, prevent the adhesion of the virus to lymphocytes and stimulate interferon which has a general antiviral effect production and may inhibit HIV infection. Current strategies in the therapy of AIDS include antiretroviral drugs and complementary nutritional support considered beneficial. Nutrition is a fundamental part of a comprehensive package of care for people living with HIV/AIDS and mushrooms supply known bioactive molecules that may help HIV positive patients.


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How to Cite

FERNANDES, P. D. T., Chaquisse, E. ., & Ferrão, J. . (2020). HIV and the Antiviral Role of Mushroom Nutraceuticals. European Journal of Applied Sciences, 8(3), 64–100.