Gas-phase Oxidation of Piperidine by "Green Oxidants" H2O2 and N2O


  • Tofik Nagiev ANAS Institute of Catalysis and Inorganic Chemistry named after acad. M.F.Nagiev
  • Nahmad Ali-zadeh
  • Inara Nagieva



hydrogen peroxide, nitric oxide (1), coherent synchronization of reactions, green oxidant, 2,3,4,5-tetrahydropyridine


Reactions of piperidine oxidation by hydrogen peroxide and nitrogen oxide (1) were investigated experimentally in the gas phase and at atmospheric pressure without the use of catalysts. The reaction site for selective oxidation of piperidine by hydrogen peroxide and nitric oxide (1) was identified, and consequently, optimal conditions for obtaining pyridine and 2,3,4,5-tetrahydropyridine from piperidine were revealed. Effect of the process parameters on reaction determinants in coherently synchronized reactions of piperidine dehydrogenation and decomposition of hydrogen peroxide and nitric oxide was demonstrated (1).


Нагиев Т.М. Химическое сопряжение. М.: Наука. 1989. 216 с.

Нагиев Т.М. Взаимосвязанные реакции и химическая интерференция. “Журнал

физическая химия”, 1994, Т.68, №3, с.456-460.

Нагиев Т.М. Взаимодействие синхронных реакций в химии и биологии Баку: Элм.

403 с.

Nagiev T.M. Coherent Synchronized Oxidation by Hydrogen Peroxide. Amsterdam:

Elsevier. 2007. 325р.

Ali-zadeh N.I., Nagieva I.T., Babaeva B.T. et al. Oxidation of Pyridine Basess by Hydrogen

Peroxide //Journal of Chemical and Chemical Engineering. 2011. v.5. №1. p.82-88.

Ali-zadeh N.I., Nagieva I.T., Babayeva B.T. et al /Oxidation of Pyridine Bases by Hydrogen

Peroxide. 19th International congress of Chemical and Process Engineering. CHISA 2010.

Prague Czech Republic. p1.21 p.179.

Ali-zadeh N.I., Nagieva I.T. Nagiev T.M. Coherent-Synchronized Oxidation of

-Ethylpyridine and Piperidine by Hydrogen Peroxide. // Journal of Chemical and Chemical

Engineering. 2013. v. 7. p. 76–80.

Nagieva I.T., Ali-zadeh N.I., Nagiev TM.“Coherent-synchronized gas-phase oxidation of

piperidine with H2O2 and N2O 4th European Organic Chemistry Congress. March 01-03.

London. England. Scientific program. P. 4/9.

Nagieva I.T., Ali-zadeh N.I., Bakhramov E.S., Nagiev TM.“Green Oxidants” - H2O2 and

N2O in the selective oxidation of pyridine bases to obtain precursors of pharmaceutical

Products. 50th General Assembly, 47th IUPAC World Chemistry Congress. Paris. France

(ORAL) 7-12 July 2019. Р1310.




How to Cite

Nagiev, T., Ali-zadeh, N., & Nagieva, I. (2022). Gas-phase Oxidation of Piperidine by "Green Oxidants" H2O2 and N2O. European Journal of Applied Sciences, 10(3), 201–208.