The Mathematical Model for Drug Delivery Through Skin

  • Nourelhoda Medhat Mahmoud Biomedical Engineering Department Faculty of Engineering Minia University Minia, Egypt
  • Ziad Tarek Alshafee Biomedical Engineering Department Faculty of Engineering Minia University Minia, Egypt
Keywords: Biomedical Applications, Medications, Mathematical model, Skin


Delivery of the medications is one of the important biomedical applications. It has significant importance for patients. There are a lot of methods for delivery of drugs such as oral, topical, sublingual, inhalation, and nasal and injection routes. Patients are suffering from needles every time they want to take their medications. The oral route is suitable and has the lowest cost, but some drugs can cause gastrointestinal tract irritation and has low bioavailability. Delivery of the medications through skin is the most suitable for patient because it is needleless without any pain for patients. Some medications have large size. Mathematical model for transportation of large molecules of medications and drugs through the skin is described. This model provides a significant reduction of medical complications and improvement in patient compliance. One of the most important parameter is the optimization of the response time of this model. The model shows good stability and response.

Author Biographies

Nourelhoda Medhat Mahmoud, Biomedical Engineering Department Faculty of Engineering Minia University Minia, Egypt

Assistant Professor

Biomedical Engineering Department
Faculty of Engineering
Minia University
Minia, Egypt

Ziad Tarek Alshafee, Biomedical Engineering Department Faculty of Engineering Minia University Minia, Egypt

Undergraduate Student

Biomedical Engineering Department
Faculty of Engineering
Minia University
Minia, Egypt


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How to Cite
Mahmoud, N. M., & Alshafee, Z. T. (2018). The Mathematical Model for Drug Delivery Through Skin. Journal of Biomedical Engineering and Medical Imaging, 5(2), 01.