https://journals.scholarpublishing.org/index.php/JBEMi/issue/feed Journal of Biomedical Engineering and Medical Imaging 2021-09-10T05:10:42+00:00 Victoria Bloom jbemi@scholarpublishing.org Open Journal Systems <p>Journal of Biomedical Engineering and Medical Imaging is peer-reviewed open access bi-monthly on-line journal that provides a medium of the rapid publication of original research papers, review articles, book reviews and short communications in the field of bio-medical engineering; medical imaging, analysis and processing. It encourages interdisciplinary research and development activities in an international environment.</p> https://journals.scholarpublishing.org/index.php/JBEMi/article/view/10781 Pattern of Alpha Fetoprotein and Activities of Liver Enzymes in Type 2 Diabetic Patients Attending Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria. 2021-08-20T10:15:09+00:00 Emmanuel Chukwuemeka Ogbodo augustinee442@gmail.com Ifeoma Priscilla Ezeugwunne augustinee442@gmail.com Stephen Shehu Idris augustinee442@gmail.com Wurola Serah Nnaemeka augustinee442@gmail.com Obinna DavidIbimere augustinee442@gmail.com Nwanneka Victoria Elosuba augustinee442@gmail.com Blessing K. Myke-Mbata augustinee442@gmail.com Ukamaka Edward augustinee442@gmail.com Johnjude Chinonso Nnamdi augustinee442@gmail.com Eberechi D. Nwanguma augustinee442@gmail.com <p>Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia, which has become health problem of global interest, linked to renal disease. The study is to assess the activities of some liver enzymes and alpha fetoprotein level in type 2 diabetic patients. 81 participants comprised 38 diabetics and 43 controls were randomly recruited. Informed, oral and written consent was obtained from the participants. Ethical approval was obtained. 6mls of fasting blood samples were collected. Plasma glucose, alpha feto-protein (AFP) levels; serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT) activities were analyzed using standard laboratory methods.&nbsp; The results showed significantly increased plasma glucose level in the diabetics than in controls (p=0.000), as well as in male diabetics than in female diabetics (p=0.048). But, the mean age, AFP, ALT, AST, ALP and GGT activities&nbsp; were the same in the diabetics and the controls; and in male and female diabetics&nbsp; at p&gt;0.05 in each case. Relatively strong positive significant correlation was observed between ALT Vs AST (r=0.566; p=0.000) and a weaker negative association exist between ALT Vs Age (r= -0.353; p=0.022) in diabetics but no associations were observed with other parameters studied. In conclusion the positive association between ALT and AST may reveal transaminase derangements in liver status of type 2 diabetic subjects studied.</p> 2021-09-10T00:00:00+00:00 Copyright (c) 2021 Emmanuel Chukwuemeka Ogbodo, Ifeoma Priscilla Ezeugwunne, Stephen Shehu Idris, Wurola Serah Nnaemeka, Obinna DavidIbimere, Nwanneka Victoria Elosuba, Blessing K. Myke-Mbata, Ukamaka Edward, Johnjude Chinonso Nnamdi, Eberechi D. Nwanguma