Cancer of the Larynx: A Brief Overview with Case Studies


  • B A Bulbulia Garden city clinic (GCC) Johannesburg South Africa
  • M R Ahmed Garden city clinic. Johannesburg South Africa



laryngeal carcinoma, trans-oral resection, organ preservation, total laryngectomy, biological markers, chemoradiation


Laryngeal cancer (LC) is globally a common malignancy affecting the the head and neck (HN) region. It occurs in the aero digestive tract and is the second most common tumour affecting the (HN) area. Squamous cell carcinoma (SCC) make up to 96% of LC. The surgical removal of LC remains an important modality of treatment. Therapeutically chemo-radiation therapy is incorporated in early and late stages of the disease and has been a game changer in preserving laryngeal organ function. Advances in endoscopic  laser technology with trans-oral resection  (TOR) of many cancers reduces morbidity and preserves laryngeal function.Treatment modalities include immunotherapy (biological) and targetting cancer cells (target therapy) to prevent cancer cell multiplication. Genetic biomarkers are unravelling newer information of the disease (LC). Risk modification factors for LC are cessation of smoking and  discouraging the use of alcohol products.




How to Cite

Bulbulia, B. A., & Ahmed, M. R. (2024). Cancer of the Larynx: A Brief Overview with Case Studies. British Journal of Healthcare and Medical Research, 11(1), 255–262.