Parkinson’s Disease and Food Expenditure in Italy: Stochastic and Non-Stochastic Analyses of Food Elements

Authors

  • Umberto Cornelli Department of Molecular Pharmacology and Therapeutics, Loyola University School of Medicine-Chicago Piazza Novelli 5, 20129 Milan Italy
  • Enzo Grossi Villa Santa Maria Foundation, Tavernerio CO Italy
  • Martino Recchia Department of Epidemiology and Clinics Biostatistics, Mario Negri Institute Alumni Association, Via Salaino 8 20144 Milan Italy
  • Claudia Antonelli ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Luca Battaglia ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Giorgia Bonalume ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Roberto Butti ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Camurri, Matteo ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Carluccio, Beatrice ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Clementi, Camilla ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Condoleo, Federico ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • D’Ambrosio, Alessio ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • De Lucia, Veronica Giardinetti Rebecca
  • Giardinetti, Rebecca ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Gusperti, Greta ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Idonia, Marco ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Idonia, Luca ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Iftime, Maria Daniela ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Malnati, Sofia ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Mandelli, Kevin ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Masini, Chiara ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Messina, Beatrice ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Nebbia, Stefano ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Piarulli, Gabriele ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Piccinini, Daniele ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Pelucchi, Francesca ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Radici, Alessandro ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Rattaggi, Matteo ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Testa, Mattia ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Volpi, Viviana ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy
  • Zahra, Meerab ITS Nuove tecnologie della Vita, Viale Europa 15, 20145 Bergamo, Italy

DOI:

https://doi.org/10.14738/aivp.121.16300

Keywords:

Parkinson's Disease, Mediterranean diet, Standardized Moertality Ratio, Neuronal mapt

Abstract

Background: The correlation between food and Parkinson's disease (PD) shows that the Mediterranean diet (MeD) brings positive benefits. Objective: To find the correlation between PD and food components in the various regions of Italy in 2016. Methods: The protein, fat, mineral and vitamin content of 275 foods belonging to 56 distinct food categories were correlated with PD in terms of standardised mortality ratio (SMR). Data were computed for 19,500 families in 540 Italian municipalities for 2016. Life expectancy, demographic data and level of well-being were also analysed. Stochastic and non-stochastic analyses (neural network mapping) were used to compute the associations with PD. Results: The following results were obtained by focusing on the food components deemed significant in both stochastic and non-stochastic analyses:  Alcohol, saturated and monounsaturated fats, calcium and sodium were found to be causative or partially causative factors. Soluble sugars, carbohydrates, starch, selenium and vitamin D were seen to be protective or partially protective. The SMR of PD was significantly lower in Southern Italy than in the North due to a lower consumption of causative foods and higher consumption of protective ones. Furthermore, the lower gross domestic product (GDP) in the South may also have a significant effect.  Conclusions: In 2016, the PD death rate in Southern Italy was significantly lower than in the North. The food component pattern that emerged in Southern regions was also significantly different: a lower consumption of causative food components and higher consumption of protective ones together with a lower GDP and life expectancy.  Using data on food expenditure and quantities enable us to track the correlation with PD SMR on an annual basis.

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Published

2024-02-01

How to Cite

Cornelli, U., Grossi, E., Recchia, M., Antonelli, C., Battaglia, L., Bonalume, G., Butti, R., Camurri, M., Carluccio, B., Clementi, C., Condoleo, F., D’Ambrosio, A., De Lucia, V., Giardinetti, R., Gusperti, G., Idonia, M., Idonia, L., Iftime, M. D., Malnati, S., Mandelli, K., Masini, C., Messina, B., Nebbia, S., Piarulli, G., Piccinini, D., Pelucchi, F., Radici, A., Rattaggi, M., Testa, M., Volpi, V., & Zahra, M. (2024). Parkinson’s Disease and Food Expenditure in Italy: Stochastic and Non-Stochastic Analyses of Food Elements. European Journal of Applied Sciences, 12(1), 195–212. https://doi.org/10.14738/aivp.121.16300