Neonatal lupus : 5 pediatric cases
DOI:
https://doi.org/10.14738/jbemi.91.11869Keywords:
Neonatal lupus erythematosus, congenital heart block, antinuclear antibodies, newbornAbstract
Neonatal lupus erythematosus is a rare condition that manifests itself in different types of damage, whether cutaneous, hepatic, hematological, neurological or even cardiac. We report here three cases of neonatal lupus occurring in newborns, two of them from completely asymptomatic mothers and revealed by cardiac involvement and one case revealed by skin involvement.
References
Silverman E, Jaeggi E (2010) Non-cardiac manifestations of neonatal lupus erythematosus. Scand J Immunol 72: 223–225
Inzinger M, Salmhofer W, Binder B (2012) Neonatal lupus erythematosus and its clinical variability. J DtschDermatolGes 10: 407–
Hulsmann AR, Oranje AP (2014) Educational paper: neonatal skin lesions. Eur J Pediatr 173: 557–566
Brucato A, Cimaz R, Stramba-Badiale M (2002) Neonatal lupus. Clin Rev Allergy Immunol 23: 279–299
Lee LA (1990) Maternal autoantibodies and pregnancy - II: the neonatal lupus syndrome. BaillieresClinRheumatol 4: 69–84
Zuppa AA, Riccardi R, Frezza S, Gallini F, Luciano RM, Alighieri G, Romagnoli C, De Carolis S (2017) Neonatal lupus: follow-up in infants with anti-SSA / Ro antibodies and review of the literature. Autoimmun Rev 16: 427–432
Brito-Zerón P, Izmirly PM, Ramos-Casals M, Buyon JP, Khamashta MA (2015) The clinical spectrum of autoimmune congenital heart block. Nat Rev Rheumatol 11: 301–312
Ambrosi A, Sonesson SE, Wahren-Herlenius M (2014) Molecular mechanisms of congenital heart block. Exp Cell Res 325: 2–9
Izmirly P, Saxena A, Buyon JP (2017) Progress in the pathogenesis and treatment of cardiac manifestations of neonatal lupus. Curr Opin Rheumatol 29: 467–472
Martin TA (2014) Congenital heart block: current thoughts onmanagement, morphologic spectrum, and role of intervention. Cardiol Young 24 (Suppl 2): 41–46
Saxena A, Izmirly PM, Mendez B, Buyon JP, Friedman DM (2014) Prevention and treatment in utero of autoimmune-associated congenital heart block. Cardiol Rev 22: 263–267
Klein-Gitelman MS (2016) Neonatal lupus: what we have learned and current approaches to care. CurrRheumatol Rep 6:60 PM
Epstein AE, JP DM, Ellenbogen KA, Estes NA 3rd, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO, Tracy CM, Epstein AE, Darbar D, JP DM, Dunbar SB, Estes NA 3rd, Ferguson TB Jr, Hammill SC, Karasik PE, Link MS, Marine JE, Schoenfeld MH, Shanker AJ, Silka MJ, Stevenson LW, Stevenson WG, Varosy PD, American College of Cardiology Foundation; American Heart Association Task Force on Practice Guidelines, Heart Rhythm Society (2013) (2012) ACCF / AHA / HRS focused update incorporated into the ACCF / AHA / HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation / American Heart Association task force on practice guidelines and the Heart Rhythm Society. J Am CollCardiol 61: e6 – e7
WallingHW, SontheimerRD (2009) Cutaneous lupus erythematosus: issues in diagnosis and treatment. Am J
lin Dermatol 10: 365–381
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 hasna aamri
This work is licensed under a Creative Commons Attribution 4.0 International License.
